I am a postdoctoral research fellow in the Center of Immunology and Inflammatory disease at Massachusetts General Hospital working within the Anthony and Conroy Labs. I specialize on conducting research in the fields of immunology and glycoscience, primarily studying the influence of N-linked glycosylation in health and human diseases. My biochemical engineering background has proven invaluable as I have transitioned into biomedical research.

The primary focus of my research is to elucidate the influence of IgG and IgE antibody glycosylation in the context of allergy. My main research projects are split into 2 facets: an R01 funded project on antibody glycosylation as it pertains to atopic dermatitis to understand the IgE-neuroimmune axis, as well as into drug allergy to study the structure and function of cephalosporin in IgE mediated drug allergy. I have been awarded NIH T32 funding to study further study drug allergy understand the mechanism involved in cephalosporin mediated anaphylaxis, for which little is known. This work has also led to additional U01 funding, allowing for a deeper exploration of these mechanisms. While our work is still in the early stages, we have been able to find specific phenotypes involved in the sialylation of IgE in disease state producing a proinflammatory allergic response, data that is mirror translationally between mouse and human samples. We have identified key IgG therapeutic mechanisms that protect against anaphylaxis as well.

Besides research, I have maintained a strong focus on education and scientific dissemination. I've had the opportunity to teach undergraduate courses in chemical engineering and aim to teach more courses during my post-doctoral tenure. As a member of the Scientific Advisory Board for Technology Network Biopharma I contribute expertise in several educational articles on topics related to biomanufacturing, cell therapy as well as immunology for a general audience. This advisory role also provides valuable opportunities to engage with other academic and industry professionals outside my area of expertise, identify emerging scientific trends, and contribute to the advancement and broadening of research in my field. My involvement in these activities reflects my dedication to fostering knowledge exchange and promoting scientific literacy within both academic and industry settings.

I am excited to continue pushing the boundaries of immunology and glycobiology research during my tenure as a post-doctoral research fellow until I start my faculty search to become a principal investigator of my own lab, where I plan to continue studying glycosylation in health and disease. I am currently working on understanding the role of IgE glycosylation different diseases. My goal is to leverage my interdisciplinary background to make meaningful contributions to the field immunology, ultimately producing therapeutics to improving patient care.